I took these boots to Denali in Alaska during the beginning of June and have nothing but good things to say. Very solid and warm, cold weather mountaineering boots. They have a simple and easy design with a lace up removable liner with two 2" wide velcro straps across the front and a waterproof zipper on the external build in gaiter sealing everything up.
The only issue, if you can call it that, is that I had hot feet on the lower mountain. I would just unzip the gaiter and role them down to let some heat out while on the move. Once reaching camp I would have to pull the liners to let them dry out. My down camp booties would easily slide in so I was still able to walk around camp freely and let my liners dry completely.
Other possible issue is the laces. If they come undone and the weather is unpleasant your fingers will freeze as you cannot tie them with larger gloves on. Others have a boa style that can be adjusted with the twist of a knob however you are forced to bring a repair kit just incase it breaks and that cannot be done with mitts either. And there is always cordage around to replace a lace if one breaks. Pick your battle here.
I used a fully strap-on style crampon (with a longer strap) so I can't say for sure, but the toe welts appear to be shallow for an automatic or semi-automatic style crampon.
My foot measures 265mm putting me in a size 42 however I purchased a 43.5 allowing for extra room for thicker socks. I would say I would not need to size up that much as my feet were never cold even on the -25 degree C days. Also the liners do pack out a bit so be sure to wear them a hand full of times before your expedition to work out any snug spots. Blisters and hot spots never even crossed my mind as they are super soft and comfortable once they have been on your feet for a few days.